Transcriptomics Analysis and How it Helps in Clinical Research
What is transcriptomics? Transcriptomics is the study of transcriptomes i.e., the entire set of RNA transcripts produced by genome under specific conditions in…
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How NGS is Helping in Discovering New Drug Targets for Cancer
Introduction The next-generation sequencing (NGS) has become one of the best approaches in the field of therapeutic diagnosis and treatment. With the help…
Role of Bioinformatics in Molecular Biology Research
Introduction Molecular biology, as the terminology describes, is the study of life at molecular level. It is the field of science that is…
Cancer Pharmacogenomics
What is Cancer Pharmacogenomics? Pharmacogenomics is the study of genetic factors that influence drug efficacy and toxicity. These studies aim to elucidate the…
Cancer Genomics
What Is Cancer Genomics? The 21st century is the era of technology and innovation. With advancements in techniques and the development of high…
ChIP-Seq: Finding Transcription Factor Binding Sites
What are Transcription Factor Binding Sites? Gene expression regulation is done by transcription factors (TFs). They control the transcription of genes and hence…
ATAC-Seq: Finding Open Chromatin Regions
Understanding Open Chromatin Regions (OCr) The DNA is a highly condensed molecule that reaches its final form after going through three hierarchies i.e.,…
Enrichment Analysis: Gene Ontology and KEGG Pathways Analysis
Introduction: The turn of the millennium has brought many high-throughput ‘omics’ techniques which have resulted in the generation of a huge amount of…
Single Cell RNA-Seq
What is Single-Cell RNA-Seq (scRNA-seq)? Single-cell RNA Sequencing technology is a high-throughput method to understand gene expression at the resolution of single cells.…
Computational Drug Discovery
Introduction New pharmaceutical drugs are developed through a systematic process of “Drug Discovery”. We know that the recent decade has seen the development…
Components Of Innate Immunity
The components of the innate immune system includes: Epithelial cells and Sentinel cells in tissues (macrophages, dendritic cells, mast cells, and others), Innate…
Features of the Innate Immune Response
General Features and Specificity of Innate Immune Responses The two principal types of reactions of the innate immune system are inflammation and antiviral…
Introductory Overview of the Immune System
Overview of Immune Responses to Microbes ⦁ Early Innate Immune Response to Microbes ⦁ Adaptive Immune Response ⦁ Initiation of Adaptive Immune Response…
