BioCode is introducing a revolutionary efficient large-scale protein-ligand docking service, CompoundHunter, that provides a quick and efficient way to identify top lead compounds for your research hypothesis. 

What is Molecular Docking

Molecular docking is a bioinformatics modeling technique that predicts the stable pose resulting from the interaction of two or more molecules. It is a crucial tool for designing new drugs targeting therapeutic biomarkers. This technique utilizes the binding properties of the ligand and target to determine the three-dimensional structure of the complex. By employing a scoring function within the software, molecular docking generates and ranks various potential adduct structures, grouping them together.

Ligands are the chemical compounds that interact with a biological target without disturbing its natural 3D conformation. Protein–ligand docking predicts the position and orientation of a ligand (a small molecule) when it is bound to a protein receptor or enzyme. Protein-ligand interactions are fundamental to many biological processes. The functions of a protein can be regulated by binding to ligands. A protein can have conformational changes under physiological conditions, which in turn are responsible for the conformational transitions among low- and high-affinity states for the ligands. Ligand binding can stabilize the protein in some specific states and thereby switch the protein among states of different functions.

Are you tired of spending countless hours on laborious protein-ligand docking research?

BioCode introduces CompoundHunter, the game-changing solution that will transform your research experience. With our revolutionary service, you can efficiently identify top lead compounds for your research hypothesis in a fraction of the time. Say goodbye to tedious manual work and let CompoundHunter handle the hassle for you!

With our advanced technology implemented in CompoundHunter, you can get your protein(s) docked against over 11,000 pre-existing ligands or custom provided ligands of your choice within just 24 hours, which would take thousands of hours for you to complete — let us handle all that hassle!

Developed By BioCode

CompoundHunter is conceptualized and developed by Waqar Hanif (CEO, BioCode) to facilitate molecular docking at a scale.

CompoundHunter Uses Compounds

• FDA & EMA approved for almost all diseases
• Antibiotic resistance, cancer therapeutics, antiviral and more

Note: All you have to do is provide the sequence(s) or PDB file of your protein(s).

Why CompoundHunter

Our protein-ligand molecular docking service offers a comprehensive pipeline that allows for the identification of the best lead compounds for various applications, including oncoproteins, antibiotic-resistant proteins, and any disease that you may be working on. Our technology is designed to deliver highly accurate results, ensuring that you can confidently move forward with your research and development. 

With our protein-ligand docking service, CompoundHunter, you can save time and resources while accelerating the progress of your research project. Trust us to deliver high-quality results, backed by years of experience and cutting-edge technology. Try our service today and take your research to the next level!

Based on AutoDock Vina

Traditionally, it would take thousands of years to dock thousands of ligands against a single protein structure, therefore we have developed a revolutionary docking service, CompoundHunter, that implements AutoDock Vina based on a multithreading approach to obtain the results within hours as compared to years. The pipeline implements AutoDock Vina on our high-end servers to make sure the results are efficiently generated as quickly as possible.

Expected Deliverables 

Upon completion of the protein-ligand docking process, our platform generates PNG (figures) and PDF report highlighting the top 10 lead compounds that meet your research hypothesis criteria. These reports provide detailed information (CSV) on each of the top lead compounds, including molecular structures, binding energies, and other key data points.

CompoundHunter Features

– CompoundHunter is a protein-ligand docking service that identifies top lead compounds for research projects.

– The service can dock proteins against over 11,000 pre-existing or custom provided ligands within 24 hours.

– CompoundHunter offers a comprehensive pipeline that identifies top lead compounds for oncoproteins, antibiotic-resistant proteins, and any disease.

– The technology delivers highly accurate results, generating PNG and PDF reports highlighting the top 10 lead compounds with molecular structures, binding energies, and other key data points.

– The pipeline implements AutoDock Vina on high-end servers for efficient result generation.

– Using CompoundHunter saves time and resources while accelerating the progress of research and development.

– All that is required from you is providing protein sequence or structure.

Comprehensive Pipeline for Diverse Applications: CompoundHunter is not limited to a specific research area. Our service offers a comprehensive pipeline that identifies the best lead compounds for oncoproteins, antibiotic-resistant proteins, and any disease you are working on. Empower your research hypothesis with the ability to explore a wide range of applications.

Highly Accurate Results Backed by Cutting-Edge Technology: Our technology is meticulously designed to deliver precise and reliable results. CompoundHunter utilizes the renowned AutoDock Vina on our high-end servers, ensuring that your protein-ligand docking outcomes are of the highest quality. Confidently move forward with your research and development based on the accurate insights provided.

Detailed Reports at Your Fingertips: Upon completion of the protein docking process, CompoundHunter generates comprehensive PDF reports and PNG figures that highlight the top 10 lead compounds meeting your research hypothesis criteria. Dive into molecular structures, binding energies, and other essential data points, allowing you to make informed decisions with confidence.

Trust and Credibility Matters 

At BioCode, we bring years of experience and expertise to the table. Our commitment to cutting-edge technology and delivering high-quality results has earned us the trust of researchers and scientists worldwide. Countless successful research projects have been accelerated and enhanced through CompoundHunter, propelling discoveries and breakthroughs in various fields.

Ready to revolutionize your research with CompoundHunter? 

Take advantage of this game-changing protein-ligand docking service today. Simply provide your protein sequence or structure, and our dedicated team will handle the rest. Save time, resources, and accelerate your research progress like never before!

Get in touch with us: compoundhunter@biocode.org.uk