Bioinformatics masterclass
The theory behind every analysis you run
Tools change every year. The thinking underneath them does not. This masterclass explains how sequence alignment really works and why a scoring matrix matters and what a phylogenetic tree is actually claiming. It is the part most people skip and then regret when a reviewer asks a hard question.
- 148lessons in the plan
- 31topics covered
- 720+lessons in the full library
- 6certificates along the way
Who this is for
People who run tools without knowing why
You can get BLAST to give you an answer. You cannot explain which matrix it used or why the E value matters. This fixes that.
Students sitting exams
Alignment and phylogenetics and structure prediction come up every year. Here they are explained properly with worked examples.
Anyone moving into bioinformatics
You need the vocabulary and the concepts before the practical courses make sense. Start here and the rest is much easier.
The six stages
The masterclass runs from first principles to protein structure. Each stage builds on the one before it and every explanation uses real biological examples.
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1
Stage one
Foundations and databases
What bioinformatics is for and how the major biological databases are built and searched.
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2
Stage two
Sequence analysis and alignment
Pairwise and multiple alignment and the scoring matrices behind them. Database searching explained properly.
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3
Stage three
Genes and regulation
DNA and protein analysis and protein families and gene prediction and the regulatory elements that control them.
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4
Stage four
Evolution and phylogenetics
What a tree claims and the models behind it and how trees are built and read without fooling yourself.
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5
Stage five
Protein structure
Structural features and databases and visualisation and secondary structure prediction and homology modelling and validation.
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6
Stage six
Genomics and RNA structure
Genome organisation and analysis plus RNA structure prediction to finish.
What you will understand by the end
Why an alignment scores the way it does
Scoring matrices and gap penalties stop being settings you leave alone.
How to read a BLAST result properly
You know what the E value means and when a hit is worth following up.
What a phylogenetic tree is claiming
Models and methods and the places where a tree can mislead you.
How gene prediction works
The signals a predictor looks for and why it gets things wrong.
How protein structures are solved and modelled
From experimental structures through homology modelling to validation.
Enough theory to defend your results
You can explain your methods section to a reviewer without hedging.
One membership covers the whole masterclass
This used to sell on its own for $164.99. All-Access Core is $21.74 a month, so a few months of membership costs less and gives you the practical courses alongside the theory.
Annual All Access
$199.00per year
- The complete programme
- Every other course including single-cell and ATAC-Seq and drug discovery
- 720+ video lessons in total
- Certificates for every course you finish
All-Access Core
$21.74per month
- Stages 1 to 4 in full
- The core library of 450+ lessons
- Specialist courses are not included
- Stop whenever you want
Questions people ask before they start
Is this hands-on or theory?
It is the theory. Our practical courses teach Python and R and the pipelines. Many people take this alongside them so the practical work makes sense.
Do I need a biology degree?
No. The first stage explains the field from scratch and the biology is introduced as you need it.
How long is it?
There are 148 lessons across 31 topics. Most people work through it over a couple of months.
Will it help with my exams?
Alignment and scoring matrices and phylogenetics and structure prediction are standard exam material and all of it is covered here.
Do I get a certificate?
Yes. You get a PDF certificate with a verification number when you complete it.
I bought the masterclass already. What now?
Nothing changes. Sign in and it is on your dashboard with your progress.
Understand the methods before you need to defend them
The tools will keep changing. What you learn here will still be true in ten years.
Start the masterclass for $199.00
