Intermediate Bioinformatics Course

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About This Course

Intermediate Bioinformatics Course Allows You To Develop In-demand Bioinformatics Skills

The revolutionary developments in the field of Bioinformatics has allowed us to predict the  molecular interactions for generating virtual simulations according to their molecular interactional information. It is an approach utilized in Structure Based Drug Designing (SBDD) as it predicts the ligand-protein binding and their conformation with great precision.

There are various bioinformatics tools and webservers available to predict the 3D structures of interacting biological complexes which utilizes various algorithms and scoring methods to evaluate such interactions. However, it is not everyone’s cup of tea to predict and analyze an optimal interacting docking complex.

In this course you’ll learn the in-demand Bioinformatics skills including the most commonly utilized biological databases & data retrieval and analysis, how to find conserved patterns and variable regions within sequence alignments & analysis and perform phylogenetic analysis to find out the evolutionarily related species/sequences.

You’ll also be able  to predict genes or CDS regions from raw DNA sequence, predict, visualize and evaluate 3D structures of proteins to functionally annotate the biological molecules. The Intermediate Bioinformatics Course also allows you to deal with various in-demand and highly efficient Molecular Docking & Docking complex evaluation tools/web servers. You’ll be able to draw logical conclusions about your real-time biological research.

Joining and learning from the Introductory Bioinformatics Courses can enhance your biological career by learning through various useful & informative pre-recorded lectures on Bioinformatics tools, databases and servers.

Learning Objectives

NCBI
Sequence Format
UCSC
UniProt
UCSC
PDB
ENSEMBL
InterPro
Phytozome
Pairwise Sequence Alignment & Analysis
Multiple Sequence Alignment & Analysis
Alignment Format
Sequence Analysis
Phylogenetic Analysis
Phylogenetic Tree Visualization & Analysis
Secondary Structure Prediction
Protein Analysis
Protein Family Database
Motif & Domain
Analysis
3D Structure Prediction
3D Structure Visualization
3D Structure Evaluation
Molecular Docking
Docking Complex Evaluation
Gene Prediction
PPI Database
Genomics Tools

Requirements

  • Bioinformatics Databases
  • Bioinformatics File Formats
  • Protein Databases & Analysis
  • Sequence Alignment & Analysis
  • Phylogenetic Analysis
  • Secondary Structure Prediction
  • 3D Structure Prediction
  • 3D Structure Visualization
  • 3D Structure Evaluation
  • Molecular Docking
  • Docking Complex Evaluation
  • Gene Prediction
  • PPI Database
  • Genomics Tools

Target Audience

  • The target audience for the Intermediate Bioinformatics Course are biologists, beginner or intermediate Bioinformaticians or data analysts with no or little experience in applications of computational bioinformatics and analysis.
  • However, a superficial understanding of molecular biology is expected from you before you join the course.
  • Bioinformatics is quite easy to get started in, even if you lack a proper understanding of the underlying concepts of Bioinformatics databases, servers, tools and the algorithms working behind them.

Curriculum

139 Lessons32h 6m

Bioinformatics Databases

Introduction to National Center of Biotechnology Information (NCBI)00:18:02
Exercise
Sequence Analysis00:17:59
Exercise
Sequence Retrieval from NCBI00:16:17
Exercise
PubMed Central & ENTREZ00:11:07
Exercise
GenBank: Nucleotide Database on NCBI00:06:50
Exercise
FASTA vs. GenBank00:18:26
Exercise
Gene Database: A Comprehensive Gene Database00:30:21
Exercise
NCBI Genomes & NCBI Assembly: Retrieval of Genomes00:36:14
Exercise
RefSeq Database: Retrieval of Single Reference Sequences00:11:16
Exercise
BLAST Database Searching00:25:37
Exercise
Introduction to Molecular Modeling Database00:08:07
Exercise
Database of Short Genetic Variations (dbSNP)00:12:16
Exercise
HomoloGene: Discovery of Gene and Protein Families00:06:11
Exercise
Introduction to UCSC Genome Browser & SARS-CoV-2 Viral Genome00:13:40
Exercise
Retrieve an Entire Genome & Retrieval of SARS-CoV-2 Viral Genome00:09:41
Exercise
Retrieval of Genomic Data & Annotation of SARS-CoV-2 Viral Genome00:05:30
Exercise
Table Browser & SARS-CoV-2 Viral Genome00:12:16
Exercise
Visualization of Genomic Data on the Genome Browser & SARS-CoV-2 Genome00:10:51
Exercise
UniProt BLAST – Database Searching00:12:33
Exercise
UniProt Peptide Search – Find Regions Within UniProt Database00:03:15
Exercise
Introduction to ENSEMBL00:07:50
Retrieval of a Gene-Protein-Chromosomal Region00:18:02
Exercise
Genome Assembly Retrieval and Analysis00:10:24
Exercise
Gene Analysis & Annotation00:34:40
Exercise
Variation Analysis00:24:37
Exercise
ENSEMBL BLAST/BLAT00:15:08
Regulation – Understand the Influence of Regulatory Elements on Genes00:04:19
Exercise
Comparative Genomics Analysis00:05:35
Exercise
Introduction to Phytozome00:09:39
Exercise
Interpret Plant Genome Records00:09:07
Exercise
Download an Entire Plant Genome & Proteome00:26:41
Exercise
Keyword or BLAST Search in a Plant Genome00:15:58
Exercise
UniProt Align – Pairwise & Multiple Sequence Alignment and Annotation00:03:48
Exercise
Visualize a Plant Genome Using JBrowse00:17:38
Exercise
UniRef And Retrieve Protein Clusters00:11:36
Exercise
UniParc And Find the Non-Redundant Entries00:04:59
Genome Reference Consortium (GRC)00:07:48
Exercise
BioProject00:06:40
Exercise
BioSystems00:04:16
Exercise
BioSample00:02:56
Exercise
Sequence Read Archive (SRA)00:07:15
Exercise
Introduction to Gene Expression Omnibus Database00:09:16
Gene Expression Omnibus – Platforms00:05:42
Exercise
Gene Expression Omnibus – Samples00:04:16
Exercise
Gene Expression Omnibus – Series00:04:01
Exercise
Gene Expression Omnibus – Datasets00:04:45
Exercise

Bioinformatics File Formats

Protein Databases & Analysis

Sequence Alignment & Analysis

Phylogenetic Analysis

Secondary Structure Prediction

3D Structure Prediction

3D Structure Visualization

3D Structure Evaluation

Molecular Docking

Docking Complex Evaluation

Gene Prediction

PPI Database

Genomics Tools

Evaluation

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$69.99$99.99

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Level
All Levels
Duration 32.1 hours
Lectures
139 lectures
Language
English

Material Includes

  • Step-by-step pre-recorded lectures
  • Learn any time, any where!
  • Transcription
  • Notes
  • Coding scripts
  • BioPresentations
  • Exercises
  • Automated Evaluations (MCQs)
  • 100% Authentic Certificate

Enrolment validity: 180 days

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